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You can view an example of how to accomplish this by going to: TripTych Demos – specifically this demo (requires modern WebGL browser).  Dexter Pratt's demo shows two 2-D network visualizations (mouse and human biological networks) with 3-D mappings between them to show where they are known to correlate.  This particular visualization is very powerful in highlighting where the two organisms correlate and where they do not correlate.

For background on the challenges of Model Organism translatability:  http://ec.europa.eu/research/health/pdf/summary-report-25082010_en.pdf