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A BEL Statement represents an experimental observation, generally reported in a scientific publication or unpublished experimental data. Generally, BEL Statements express a causal or correlative relationship between two biological entities. Because BEL Terms are functionally composed, a BEL Statement can consist of a single BEL Term; this simple statement indicates that the biological entity represented by the term has been observed.

Example BEL Statements

Subject Term Only

complex(p(HGNC:CCND1), p(HGNC:CDK4))

The abundance of a complex formed from protein abundances designated by CCND1 and CDK4 in the HGNC namespace. This is a subject term only statement, and indicates that the entity specified by the term has been observed.

Causal

p(HGNC:CCND1) => act(p(HGNC:CDK4))

The abundance of the protein designated by CCND1 in the HGNC namespace directly increases the activity of the abundance of the protein designated by CDK4 in the HGNC namespace.

Causal

p(HGNC:BCL2)-| bp(MESHPP:Apoptosis)

The abundance of the protein designated by BCL2 in the HGNC namespace decreases the biological process designated by apoptosis in the MESHPP (phenomena and processes) namespace.

Nested Statement - Object Term is Statement

p(HGNC:GATA1) => ( act(p(HGNC:ZBTB16)) => r(HGNC:MPL) )

The abundance of the protein designated by GATA1 in the HGNC namespace directly increases the process in which the activity of the protein abundance designated by ZBTB16 in the HGNC namespace directly increases the abundance of RNA designated by MPL in the HGNC namespace.

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